Product Name Specification Material Steel/Origin Price (Yuan/Ton) Than Yesterday Last Week, General Line Φ6.5mm Q235 Handan Steel 4810 0 -20 -50 Common Line Φ8mm Q235 Handan Steel 4810 0 -20 -50 Common Line Φ10mm Q235 Handan Steel 4810 0 -20 -50 High Line Φ6.5mm Q235 Guangzhou Steel 4820 0 -40 -70 High Line Φ6.5mm Q235 Handan Steel 4800 0 -50 -70 High Line Φ6.5mm Q335 Beitai 4680 0 -70 -150 High Line Φ6.5mm Q335 Ping Steel 4760 0 -40 -100 Rebar Φ12mm HRB335 Ma Steel 4870 0 0 0 Rebar Φ12mm HRB335 Tang Steel 4870 0 0 0 Rebar Φ18-25mm HRB335 Ma Steel 4720 0 20 10 Rebar Φ16- 25mm HRB335 Tang Steel 4760 0 20 10 Rebar Φ18-25mm HRB335 Liu Steel 4720 0 20 20 Rebar Φ18-25mm HRB335 Pyongsteel 4720 0 0 0 Rebar Φ18-25mm HRB335 Jianlong 4630 0 -10 0 Rebar Φ18-25mm HRB335 Shougang 4720 0 0 0 Rebar Φ16-25mm HRB335 Newly Asked 4650 0 0 20 Rebar Φ16-25mm HRB335 Wide Steel 4770 0 -20 -10 Rebar Φ12mm HRB335 Handan Steel 5000 0 0 70 Rebar Φ14mm HRB335 Handan 4900 0 -80 70 Rebar Φ16mm HRB335 Handan Steel 4910 0 0 140 Rebar Φ18-25mm HRB335 Handan Steel 4760 0 -10 10 Rebar Φ16-25mm HRB335 Yufeng 46 80 0 -10 -20 Threaded steel Φ16-25mm HRB335 Cold steel 4720 0 0 -20 Threaded steel Φ16-25mm HRB335 Wanxin 4700 0 0 10 Grade III rebar Φ12mm HRB400 Magang 5100 0 0 90 Grade III rebar Φ14mm HRB400 Horse Steel 5100 0 0 90 Grade III Rebar Φ16-25mm HRB400 Masteel Grade 4950 0 0 100 Grade III Rebar Φ16-25mm HRB400 Grade 5050 0 0 130 Grade III Rebar Φ16-25mm HRB400 Grade 5010 0 0 80 Class III Thread Steel Φ18-25mm HRB400 Tang Steel 4920 0 0 70 Grade III Rebar Φ18-Φ25mm HRB400 Ping Steel 4920 0 0 70 Hot Roll 2.75mm*1250*C Q235 Tong Steel 5300 0 350 350 Hot Roll 2.75mm*1250*C Q235 Bead Steel 5130 0 50 80 Hot rolled coil 2.75mm*1250*C Q235 Handan Steel 5130 0 0 80 Hot rolled coil 2.75mm*1250*C Q235 Tangsteel 5200 0 0 0 Hot rolled coil 3.0mm*1250*C Q235 Angang / Handan Steel 5080 0 -70 80 Hot Roll 3mm*1500*C Q235 Tang Steel 5100 0 0 220 Hot Roll 4.75mm*1500*C Q235 Tang 4800 0 -30 20 Hot Roll 4.75mm*1500*C Q235 Benxi Steel 4800 0 -30 20 Hot Rolled Roll 5.5mm*1500*C Q235 Tang Steel 4760 0 -20 -20 Hot Rolled Roll 5.75mm*1500*C Q235 Liu Steel 4760 0 -40 -20 Hot Rolled Roll 5.75mm* 1500*C Q235 Angang/Benc 4760 0 -40 -20 Hot Roll 5.75m m*1500*C Q235 Ma Steel 4880 0 -20 -20 Hot Roll 7.5mm*1500*C Q235 Ben Steel 4760 0 -20 10 Hot Roll 7.5mm*1500*C Q235 Tang Gang 4750 0 -30 0 Hot Rolled Volume 11.5*1500*C Q235 Tangshan Iron & Steel 4750 0 -30 20 Product Name Specification Material Steel/Origin Price (Yuan/Ton) Yesterday Last Week Last Month Strip 183-232mm*2.5 DF01 Semisteel 4800 0 0 170 Band Steel 295-355mm*2.5 DF01 Ruifeng 4700 0 -30 50 Strip 295-352mm*2.5 Q195L Tangshan Jianlong 4730 0 -20 50 Strip 275mm*2.5 Q195L Radon 4780 0 -20 50 Strip 240-255mm*2.5 Q195 Steel 4730 0 0 80 Strip 255mm*2.5 Q235 Tianjin Roll 4770 0 -30 40 Strip 352mm*2.75 Q235 Tang 4730 0 -20 50 Strip 434mm*3.0 Q235 Tang 4730 0 -20 50 Strip 680 -720mm*5.0 HG5 Beitai 4550 0 -50 10 Strip 438-520mm*2.75 HG5 Xingye 4750 0 -20 50 Strip 680-735mm*5.0 HG5 Tingtin 4550 0 -50 10 Strip 505-700mm*2.75 HG5 Latitude 4800 0 0 20 Cold rolled coil 1.0mm*1250*2500 SPCC Angang 5850 20 20 0 Cold rolled coil 1.2mm*1250*2500 ST12 Angang 5850 20 20 0 Cold rolled coil 2.0mm*1250*2500 ST12/DC01 Angang 5850 20 20 0 Cold rolled coils 3.0mm*1250*2500 ST12/DC01 Angang 5850 20 20 -50 Cold rolled coils 1.0mm*1500*C SPCC Benxi Steel 5800 50 50 50 Cold rolled coils 1.0*1250*2500 SPCC Wugang 5830 50 50 100 Cold rolled coil 1.5mm*1250*2500 ST12 Wugang 5830 50 50 100 Cold rolled coil 2.0mm*1250*2500 ST12 Wugang 5830 50 50 100 Cold rolled coil 3.0mm*1250*2500 ST12 Wugang 5830 30 30 80 Cold rolled coil 1.0mm*1250*c ST12 Kunming Steel 5750 50 50 50 Cold Rolled coils 1.0mm*1250*c ST12 Masteel 5800 50 50 70 Cold rolled coils 1.0mm*1250*c ST12 Steel 5780 50 50 80 Puzhong 6mm Q235B Xinyu 5680 0 30 110 Puzhong 8mm Q235A Handan Steel 5630 0 30 110 Puzhong Plate 10mm Q235A Shan Steel 5330 0 30 110 Puzhong Plate 14-20mm Q235A Shan Steel 5160 0 30 110 Puzhong Plate 22-28mm Q235B Shan Steel 5160 0 30 110 Puzhong Plate 10mm Q235A Liusteel 5330 0 30 110 Puzhong board 12mm Q235A Liuzhou steel 5210 0 30 110 Puzhong board 14-20mm Q235A Liuzhou steel 5160 0 30 110 Puzhong board 8mm Q235A Xinyu 5630 0 30 110 Puzhong board 10mm Q235A Xinyu 5330 0 30 100 Puzhong board 12mm Q235A Xinyu 5210 0 30 110 Puzhong Plate 14-20mm Q235A Xinyu 5160 0 30 110 Low Alloy Sheet 8mm Q345 Handan Steel 5780 0 30 100 Low Alloy Sheet 10mm Q345 Handan Steel 5530 0 30 100 Low Alloy 12mm Q345 Handan Steel 5380 0 30 100 Low Alloy Plate 20mm Q345 Handan Steel 5360 0 30 110 Boiler Plate 6mm 20g Xinyu 5900 0 0 100 Boiler Plate 8mm 20g Liuzhou Steel 5850 0 0 100 Boiler Plate 10mm 20g Liuzhou Steel 5600 0 0 100 Boiler Plate 12mm 20g Liuzhou Steel 5360 0 0 60 Boiler Plate 14mm 20g Liuzhou Steel 5360 0 0 110 Boiler Plate 20-39mm 20g Liuzhou Steel 5700 0 0 450 Product Name Specification Material Steel/Original Price (Yuan/Ton) Than Yesterday Last Week Monthly Container Plate 8mm 16MnR Liuzhou Steel 5830 0 0 0 Container Plate 10mm 16MnR Liu Steel 5650 0 0 0 Container Plate 12mm 16MnR Liusteel/Shougang 550 0 0 0 Container Plate 14-20mm 16MnR Liusteel/Shougang 5500 0 0 0 Container Plate 22 -30mm 16MnR Liusteel/Shougang 5550 0 0 0 Container plate 8mm 16MnR Xinyu 5850 0 0 0 Container plate 10mm 16MnR Xinyu 5650 0 0 0 Container plate 12mm 16MnR Xinyu 5500 0 0 0 Container plate 14-20mm 16MnR Xinyu 5450 0 0 0 Sew Φ25*2.5 20# Wuxi 6050 0 0 100 Seamless Φ38*3 20# Xinyu 5420 0 0 100 Seamless Φ48*4 20# Xinyu 5420 0 0 100 Seamless Φ57*3.5 20# Xinyu 5420 0 0 100 seamless pipe Φ60*4 20# Xinyu 5420 0 0 100 seamless pipe Φ89*4.5 20# Guangxi 5420 0 0 100 seamless pipe Φ108*4.5 20# saddle 5250 0 0 100 Seamless pipe Φ219*7 20# Steel 5600 0 0 100 Seamless pipe Φ219*7 20# Steel 5500 0 0 100 I-beam 18#/a Q235 Sea-steel 4430 0 0 130 I-beam 25 #/a Q235 Laiwu Steel 4700 0 0 130 I-beam 25#/b Q235 Wu Steel 4810 0 0 130 I-beam 25#/b Q235 Laigang 4710 0 0 130 I-beam 36#/b Q235 Laiwu Steel 4760 0 0 130 I-beam 40#/b Q235 Laigang 4780 0 0 130 Channel 16#a Q235 Masteel 4800 0 0 200 Channel 16#a Q235 Masteel 4500 0 0 180 Channel 20# Q235 Masteel 4780 0 0 180 Channel 16#a Q235 Masteel 4800 0 0 180 Channel 20# Q235 Masteel 4910 0 0 140 40*5mm Q235 Tongsteel 4850 0 0 200 50*50*5mm Q235 Masteel 4850 0 0 200 50* 50*5mm Q235 Tong Steel 4800 0 0 200 Angle Steel 140*140*5mm Q235 Ma Steel 4860 0 0 200 Galvanized Roll 0.7mm*1000*C ST02Z Angang 5800 0 0 270 Galvanized Roll 1.0mm*1000*C ST02Z Angang 5680 0 0 330 Galvanized coil 0.7mm*1000*C ST02Z Benxi Steel 5800 0 0 270 Galvanized coil 1.0mm*1000*C ST02Z Benxi Steel 5680 0 0 330 Galvanized coil 1.0mm*1000*C DC51D+Z Benson Steel 5680 0 0 330 Galvanized coil 1.0mm*1000*C DC51D+Z Masteel 5650 0 0 300 Color coated roll 0.326mm*1200*C SGCC Taiwan Minhui 8000 0 0 0 Coil 0.376mm*1000*C SGCC Taiwan Yanhui 7900 0 0 0 Color Coil 0.5mm*1000*C SGCC Baosteel 7700 0 0 0 Color Coil 0.426mm*1000*C CGCC Shunpu 7550 0 0 0 Color Coil 0.476mm*1000*C CGCC Shunpu 7350 0 0 0
Pyrimidine series intermediates
Pyrimidine, also known as 1,3-diazepine, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by replacing 2 carbons in the meta-position of benzene with 2 nitrogen atoms, and is a diazine. Like pyridine, pyrimidine retains its aromaticity.
Introduction
Name: Pyrimidine
Molecular formula: C4H4N2
Molar mass: 80.09 g/mol
Density: 1.016 g/ml
Melting point: 20 - 22 °C
Boiling point: 123 - 124 °C
CAS Number: 289-95-2
EINECS Number: 206-026-0
SMILES: C1=NC=NC=C1
Application
(1) Anticancer drugs. In the selection of anticancer substances, it is crucial that there are significant differences between tumor tissues and normal tissues, that is, they have a certain ability to recognize target cells. Porphyrin compounds have special affinity for cancer cells due to their unique structures, and they can selectively stay in cancer tissues. The research of it as a localizing agent and a drug for diagnosis and treatment of cancer has already aroused great interest of chemists, medical scientists and biologists. 5-Fluorouracil is a widely used anti-metabolite and anti-tumor drug in clinic. It has inhibitory effect on various tumors. It has good clinical effect in the treatment of colorectal cancer, gastric cancer, breast cancer and other cancers. Polyesters, polyester hydrocarbons, polyester amides, deoxyribonucleic acid, furans, 5-fluorouracil derivatives linked to nitroxide radicals all have antitumor effects.
(2) Anti-AIDS drugs. Viral diseases have become one of the most harmful diseases to human beings, especially the spread of AIDS, which has aroused widespread concern. There are many kinds of anti-AIDS drugs that have been approved by the US Food Administration (FDA), many of which are nucleoside compounds. In order to reduce the toxicity of drugs and improve their efficacy, scientists have begun to turn their attention to the study of non-nucleoside compounds, and such compounds have become the focus of antiviral drug research.
Synthetic method
Pyrimidines and various substituted pyrimidines are synthesized in a variety of ways. For example, barbituric acid (2,4,6-trihydroxypyrimidine) can be obtained by the condensation of urea and diethyl malonate under the action of sodium alkoxide. Barbituric acid and phosphorus oxychloride are heated together to obtain 2,4,6-trichloropyrimidine, which reacts with sodium methoxide to obtain trimethoxypyrimidine. Chloropyrimidines react with ammonia or primary and secondary amines to generate the corresponding aminopyrimidines. The derivatives of pyrimidine, cytosine, uracil and thymine, are the constituent parts of nucleic acid and deoxynucleic acid, and the pyrimidine part in the vitamin B1 molecule is a 4-amino-2-methyl-5-pyrimidine methyl group. Many oral long-acting sulfa drugs are derivatives of pyrimidine and its isomers.
The 2,4-dichloropyrimidine is prepared by reduction reaction in the presence of palladium, magnesium oxide and activated carbon.
Pyrimidine Series Intermediates,2-Chloro-5-Methylpyrimidine,5-Bromo-2-chloropyrimidine,2 4-Dichloro-5-Methylpyrimidine
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